Precision medicine has revolutionized certain areas of healthcare in developed countries, such as cancer treatment. Tools such as big data, consumer monitoring, gene sequencing and more are having a deep, lasting impact in the way we approach patients: from one-size-fits-all to personalized interventions. Could it be possible to apply the same principle to global health? Could the increasing wealth of epidemiological and population information and smarter strategic interventions reduce the burden of disease and the toll of premature death in the most affected areas of the world? Global Health scholars, under leadership of Professor Flahault, Director of the Institute of Global Health in Geneva (one of the 17 members of EGHRIN), think so. They published a roadmap on this topic in the Journal of Public Health and Emergency, which can be read here.